TA

Thymosin Alpha-1
• Chemical Nature: Thymosin Alpha-1 is a 28-amino acid synthetic peptide derived from Thymosin Fraction 5, found in the thymus gland.
• Molecular Formula: C₁₄₀H₂₂₈N₄₀O₅₆
Mechanism of Action

• Immune Modulation: Thymosin Alpha-1 enhances the function of T cells, a critical component of the adaptive immune system. It stimulates the maturation and activation of T cells, particularly T helper cells (Th1), which play a key role in immune responses.
• Toll-Like Receptor (TLR) Interaction: Thymosin Alpha-1 interacts with Toll-like receptors (TLRs), particularly TLR2, TLR4, and TLR8, promoting the release of key cytokines such as IL-2 and interferon-α, which are essential for immune cell activation and proliferation.
• Dendritic Cell Activation: Thymosin Alpha-1 promotes the differentiation and activation of dendritic cells, which are crucial for initiating and maintaining immune responses.
• Enhanced Antiviral and Antibacterial Defense: By promoting a Th1 immune response, Thymosin Alpha-1 enhances the body’s ability to combat intracellular pathogens, including viruses and certain bacteria.